Smoking cessation interventions in COPD a network meta-analysis of randomised trials / R. Strassmann (2009)  

Public Titre : Smoking cessation interventions in COPD a network meta-analysis of randomised trials : a network meta-analysis of randomised trials Type de document : texte imprimé Auteurs : R. Strassmann, Auteur ; B. Bausch, Auteur ; J. Kleijnen, Auteur ; O. Braendli, Auteur ; A. Spaar, Auteur ; M.A. Puhan, Auteur Editeur : European Respiratory Society (ERS) Année de publication : 2009 Collection : European Respiratory Journal num. 34 Importance : p. 634-640 Présentation : tab. Langues : Anglais (eng) Catégories : [TABAC] étude [TABAC] sevrage tabagique:aide au sevrage:conseil de sevrage [TABAC] sevrage tabagique:efficacité du sevrage [TABAC] sevrage tabagique:méthode de sevrage:méthode individuelle:approche pharmacologique:substitution nicotinique [TABAC] tabagisme:pathologie:pathologie respiratoire:broncho-pneumopathie chronique obstructive Index. décimale : TA 6.2 Méthodes individuelles Résumé : The aim of this study was to rank order the effectiveness of smoking cessation interventions for chronic obstructive pulmonary disease (COPD) patients. We searched 10 databases to identify randomised trials of smoking cessation counselling (SCC) with or without pharmacotherapy or nicotine replacement therapy (NRT). We conducted a network meta-analysis using logistic regression analyses to assess the comparative effectiveness of smoking cessation interventions while preserving randomisation of each trial. The analysis of 7,372 COPD patients from six out of eight identified trials showed that SCC in combination with NRT had the greatest effect on prolonged abstinence rates versus usual care (OR 5.08, p<0.0001) versus SCC alone (2.80, p = 0.001) and versus SCC combined with an antidepressant (1.53, p = 0.28). The second most effective intervention was SCC combined with an antidepressant (3.32, p = 0.002) versus SCC alone (1.83, p = 0.007), with no difference between antidepressants. SCC alone was of borderline superiority compared with usual care (1.81, p = 0.07). A small body of evidence suggests that SCC combined with NRT is more effective than other combinations and single smoking cessation treatments in COPD, but substantially more research is needed for this most important COPD treatment. En ligne : https://erj.ersjournals.com/content/34/3/634 Permalink : https://biblio.fares.be/opac_css/index.php?lvl=notice_display&id=8078

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